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St. John’s Wort CO2-to extract, 10 % Hyperforins
Product-No.: 028.002

Further product-related documents are available on request

Raw Material:
Hypericum perforatum – Twigs with flowers, dried

Production:
By supercritical fluid extraction with natural carbon dioxide, no solvent residues, no inorganic salts, no heavy metals, no reproducible microorganisms [1]. The extract is standardized by addition of MCT-oil and stabilized with natural tocopherol.

Ingredients:
see specification

Application:
St. John’s wort is used in herbal medicinal products for the treatment of mild to moderate depressive phases, as well as for the short-term symptomatic treatment of mild depressive disorders [2].*

Due to the enrichment of Hyperforin in the extract, we cannot exclude the possibility of classification as a novel food according to Regulation (EU) 2015/2283. Also, we currently have no reliable evidence of significant consumption of the extract before 15.05.1997.*

St. John’s wort extract is rich in hyperforin, which has an antimicrobial and anti-inflammatory effect. It also helps to reduce water loss from the skin. As a result, the extract can be used in various skin care products for sensitive, irritated, dry and impure skin [3].*

Literature:
[1] P. Manninen, E. Häivälä, S. Sarimo, H. Kallio : Distribution of microbes in supercritical CO2 extraction of sea buckthorn (Hippophae rhamnoides) oils : Zeitschrift für Lebensmitteluntersuchung und -Forschung / Springerverlag (1997) 204: 202-205
[2] Committee on Herbal Medicinal Products (HMPC), European Medicines Agency (EMA) : COMMUNITY HERBAL MONOGRAPH ON HYPERICUM PERFORATUM L., HERBA (WELL-ESTABLISHED MEDICINAL USE) : (2009) EMA/HMPC/101304/2008
[3] U. Wölfle, G. Seelinger und C. M. Schempp : Topical Application of St. Johnʼs Wort (Hypericum perforatum) : Planta Med 2014, 80: 109–120

* Statements summarise literature evidence and have informative character. They might be derived from in vitro or animal tests and thus not be substantiated for humans. Statements have not been evaluated by competent authorities and do not refer to finished products. The marketer of any finished product containing any FLAVEX extract as ingredient is responsible for assuring that the claims made for his product are lawful and comply with all applicable laws and regulations of the country in which the product is to be sold.